Postdoctoral Fellowship at NIH

A postdoctoral position is available at the NIH in Henry Levin's lab.

Position Title: Genomic and bioinformatic studies of transposable elements and HIV-1

Position Description: A postdoctoral position is available to study the mechanisms and impact of Long Terminal Repeat-retrotransposons and retroviruses. The LTR-retrotransposon Tf1 in the fission yeast Schizosaccharomyces pombe is structurally similar to retroviruses and uses mechanisms of reverse transcription and integration that are excellent models for retrovirus replication. Saturated profiles of integration sites revealed Tf1 inserts into the promoters of stress response genes. Current work focuses on understanding how integration sites are selected and how integration promotes adaptation to changes in environment. To identify common mechanisms of integration we generate large-scale datasets of HIV-1 integration in human cells and analyze genome-wide patterns of integration. Research is also conducted on other transposable elements to develop technology capable of generating genome-wide profiles of gene function. Further details and a list of publications can be found at: https://science.nichd.nih.gov/confluence/display/pcrm/Henry+Levin

Interested candidates must have a Ph.D. and/or an M.D. and have a strong background in molecular biology, genetics, or virology. Bioinformatic and programming skills will be of great benefit. To apply submit a cover letter, curriculum vitae, bibliography, and names of three references to:

Dr. Henry Levin
Eunice Kennedy Shriver National Institute of Child Health and Human Development
National Institutes of Health
Bld 18T, room 106
Bethesda, MD, 20892
E-mail: henry_levin@nih.gov

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